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Structure of 90390-11-7
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N-Methyl-1-(4-(trifluoromethyl)phenyl)methanamine is a bench-stable, moisture-tolerant amine featuring a para-trifluoromethyl aryl group that imparts strong electron-withdrawing character. This structure enables efficient coupling in C–N bond formation and serves as a key building block for bioactive molecules in medicinal chemistry.
N-Methyl-1-(4-(trifluoromethyl)phenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amine functionalization. Its trifluoromethylated aryl group enhances metabolic stability and lipophilicity, while the N-methylated primary amine facilitates downstream derivatization via alkylation, acylation, or reductive amination. The compound exhibits good bench stability and is compatible with common purification methods, making it suitable for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P264-P271-P280-P301+P330+P331-P304+P340-P363-P501
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Lot numbers can be found on the outside label of a product: