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CS-W001157 4
Total: USD 88.00

5-Thiazolamine hydrochloride

  • CAS No. 942631-51-8

  • Cat. No. CS-W006568
  • Purity≥95%
  • MDL No.MFCD10687116

*For research and further manufacturing use only, not for direct human use.

5-Thiazolamine hydrochloride|CS-W006568

Structure of 942631-51-8

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General Information

  • CAS No. 942631-51-8
  • Cat. No. CS-W006568
  • Purity ≥95%
  • MDL No. MFCD10687116
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅ClN₂S
  • Molecular Weight 136.60
  • Synonym(s) 5-AMINOTHIAZOLE HCL
  • SMILES NC1=CN=CS1.Cl

Description

5-Thiazolamine hydrochloride offers a bench-stable, moisture-tolerant platform for constructing bioactive heterocycles. This electron-deficient thiazole derivative integrates readily into medicinal chemistry campaigns, enabling efficient access to kinase inhibitors and antimicrobial scaffolds through straightforward coupling reactions under standard conditions.

Application

5-Thiazolamine hydrochloride serves as a versatile building block in medicinal chemistry, enabling direct incorporation of a thiazole scaffold into bioactive molecules. Its stable, bench-ready form facilitates straightforward functionalization via amine coupling reactions, and the retained hydrochloride salt enhances solubility and handling. Functions effectively in standard peptide coupling and heterocyclic synthesis workflows, supporting efficient access to pharmacologically relevant architectures.

Synthesis

  • Route1

    References

    • WO2007/71955 A1, ; Page/Page column 47 ; WO 2007/071955 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.1471
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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