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Ethyl 5-formyl-1H-pyrazole-3-carboxylate

  • CAS No. 93290-12-1

  • Cat. No. CS-0055100
  • Purity≥95%
  • MDL No.MFCD16620106

*For research and further manufacturing use only, not for direct human use.

Ethyl 5-formyl-1H-pyrazole-3-carboxylate|CS-0055100

Structure of 93290-12-1

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General Information

  • CAS No. 93290-12-1
  • Cat. No. CS-0055100
  • Purity ≥95%
  • MDL No. MFCD16620106
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₃
  • Molecular Weight 168.15
  • Synonym(s) Ethyl 5-ForMylpyrazole-3-carboxylate
  • SMILES O=C(C1=NNC(C=O)=C1)OCC

Description

Ethyl 5-formyl-1H-pyrazole-3-carboxylate features a reactive aldehyde group flanked by electron-deficient pyrazole and ester functionalities, enabling direct coupling in heterocyclic synthesis. This bench-stable reagent integrates efficiently into multistep sequences for advanced pharmaceutical intermediates and functional materials.

Application

Ethyl 5-formyl-1H-pyrazole-3-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to functionalized pyrazole scaffolds. The conjugated formyl and ester groups offer orthogonal reactivity—facilitating nucleophilic additions, condensations, and metal-catalyzed couplings—while maintaining bench stability and ease of purification. Its defined regiochemistry supports reliable downstream transformations in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   72.05
  • LogP   0.3989
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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