(R)-1-Boc-3-isopropyl-piperazine

Name: (R)-1-Boc-3-isopropyl-piperazine
Brand: ChemScene
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CAS No. 928025-63-2
Cat. No. CS-W020509
Purity≥97%
MDL No.MFCD07772113

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-1-Boc-3-isopropyl-piperazine|CS-W020509

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General Information

CAS No. 928025-63-2
Cat. No. CS-W020509
Purity ≥97%
MDL No. MFCD07772113
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₂₄N₂O₂
Molecular Weight None
Synonym(s) (R)-1-Boc-3-isopropylpiperazine
SMILES O=C(OC(C)(C)C)N1C[C@@H](C(C)C)NCC1

Description

(R)-1-Boc-3-isopropyl-piperazine is a stereochemically defined piperazine derivative featuring a tert-butoxycarbonyl group at the nitrogen and a sterically hindered isopropyl substituent. This configuration enhances stability and facilitates selective functionalization in synthetic workflows. The protected amine enables controlled coupling reactions, while the chiral backbone supports asymmetric synthesis applications.

Application

(R)-1-Boc-3-isopropyl-piperazine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of complex piperazine-based scaffolds. Its Boc group provides stability and orthogonal protection, facilitating selective deprotection and functionalization. The isopropyl substituent enhances steric differentiation and modulates solubility, supporting efficient purification and downstream derivatization in standard synthetic workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P301+P310-P330-P501

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Computational Chemistry Data

TPSA 41.57
LogP 1.8513
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperazine compounds

Key Words

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(R)-1-Boc-3-isopropyl-piperazine

CAS No. 928025-63-2

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