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CS-W001157 4
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(S)-1-Boc-3-isopropyl-piperazine

  • CAS No. 475272-54-9

  • Cat. No. CS-B0416
  • Purity≥98%
  • MDL No.MFCD07772112

*For research and further manufacturing use only, not for direct human use.

(S)-1-Boc-3-isopropyl-piperazine|CS-B0416

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General Information

  • CAS No. 475272-54-9
  • Cat. No. CS-B0416
  • Purity ≥98%
  • MDL No. MFCD07772112
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₄N₂O₂
  • Molecular Weight 228.33
  • Synonym(s) (S)-1-Boc-3-isopropylpiperazine
  • SMILES O=C(OC(C)(C)C)N1C[C@H](C(C)C)NCC1

Description

(S)-1-Boc-3-isopropyl-piperazine is a chiral piperazine derivative featuring a Boc-protected amine and a sterically hindered isopropyl group. This configuration enables selective incorporation into complex molecular architectures, particularly in medicinal chemistry scaffolds requiring defined stereochemistry and enhanced metabolic stability.

Application

(S)-1-Boc-3-isopropyl-piperazine serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to complex piperazine-based scaffolds. Its Boc group provides excellent stability and ease of removal under mild acidic conditions, while the isopropyl substituent enhances steric differentiation and solubility. The compound facilitates functionalization at both nitrogen atoms and supports diverse coupling reactions, making it well-suited for the synthesis of bioactive molecules and pharmaceutical intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.8513
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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