Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Boc-3-isopropyl-piperazine

  • CAS No. 502649-32-3

  • Cat. No. CS-0001883
  • Purity≥98%
  • MDL No.MFCD08273958

*For research and further manufacturing use only, not for direct human use.

1-Boc-3-isopropyl-piperazine|CS-0001883

Structure of 502649-32-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 502649-32-3
  • Cat. No. CS-0001883
  • Purity ≥98%
  • MDL No. MFCD08273958
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₄N₂O₂
  • Molecular Weight 228.33
  • Synonym(s) 1-Boc-3-isopropylpiperazine
  • SMILES O=C(OC(C)(C)C)N1CC(C(C)C)NCC1

Description

1-Boc-3-isopropyl-piperazine is a bench-stable, moisture-tolerant piperazine derivative featuring a bulky isopropyl group at the 3-position and a Boc-protected amine at the 1-position. This combination enhances solubility in organic solvents and simplifies deprotection workflows in synthetic routes. The molecule serves as a key building block for bioactive heterocycles, enabling efficient access to complex scaffolds in medicinal chemistry and drug discovery projects.

Application

1-Boc-3-isopropyl-piperazine serves as a versatile nitrogen-containing building block in medicinal chemistry, enabling efficient access to piperazine-based scaffolds. The Boc group provides stability and orthogonal deprotection under mild acidic conditions, while the isopropyl substituent enhances steric profile and modulates solubility. It functions effectively in amide couplings, reductive aminations, and transition-metal-catalyzed cross-couplings, offering predictable reactivity and ease of purification in multi-step syntheses.

Synthesis

  • Route1

    References

    • US2003/153556 A1, ; US 20030153556 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.8513
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Boc-3-isopropyl-piperazine sigma1-Boc-3-isopropyl-piperazine manufacturer1-Boc-3-isopropyl-piperazine price1-Boc-3-isopropyl-piperazine structure1-Boc-3-isopropyl-piperazine SDSbuy 1-Boc-3-isopropyl-piperazine1-Boc-3-isopropyl-piperazine supplier1-Boc-3-isopropyl-piperazine uses1-Boc-3-isopropyl-piperazine molecular weightprice of 1-Boc-3-isopropyl-piperazine1-Boc-3-isopropyl-piperazine chemical name formula of 1-Boc-3-isopropyl-piperazine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label