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Structure of 919346-89-7
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5-Bromoisoindoline hydrochloride offers a stable, moisture-tolerant platform for constructing complex heterocycles in medicinal chemistry. The bromine substituent enables direct functionalization via cross-coupling, while the protonated isoindoline core enhances solubility and handling under standard conditions. This salt form facilitates purification and integration into multi-step syntheses.
5-Bromoisoindoline hydrochloride serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the isoindoline core. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig couplings, under standard conditions. The hydrochloride salt enhances solubility and stability in polar solvents, simplifying handling and purification. This compound functions reliably in the synthesis of biologically active heterocycles and pharmaceutical intermediates, offering predictable reactivity and compatibility with common protecting groups.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: