Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Bromoisoindoline hydrochloride

  • CAS No. 923590-95-8

  • Cat. No. CS-W007793
  • Purity≥97%
  • MDL No.MFCD10700134

*For research and further manufacturing use only, not for direct human use.

4-Bromoisoindoline hydrochloride|CS-W007793

Structure of 923590-95-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 923590-95-8
  • Cat. No. CS-W007793
  • Purity ≥97%
  • MDL No. MFCD10700134
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BrClN
  • Molecular Weight 234.52
  • Synonym(s) 4-Bromo-Isoindoline Hcl
  • SMILES BrC1=CC=CC2=C1CNC2.Cl

Description

4-Bromoisoindoline hydrochloride offers a stable, moisture-tolerant platform for constructing complex heterocycles in synthetic organic chemistry. This bench-stable derivative features a brominated isoindoline core that integrates readily into cross-coupling reactions and enables direct functionalization at the 4-position. Its crystalline form simplifies handling and purification in process development workflows.

Application

4-Bromoisoindoline hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to isoindoline-based scaffolds prevalent in bioactive molecules. Its bench-stable form facilitates handling and purification, while the bromine substituent supports diverse cross-coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig couplings. Functions effectively in the synthesis of pharmaceutical intermediates and functionalized heterocycles under standard reaction conditions.

Synthesis

  • Route1
    • null|null
      923590-92-5
    • ~%
    • In-stock
      4-Bromoisoindoline hydrochloride|CS-W007793
      923590-95-8

    References

    • US2007/27071 A1, ; Page/Page column 68 ; US 20070027071 A1
  • Route2
    • 2-Benzyl-4-bromoisoindoline|CS-0321818
      923590-78-7
    • ~%
    • In-stock
      4-Bromoisoindoline hydrochloride|CS-W007793
      923590-95-8

    References

    • WO2008/51477 A2, ; Page/Page column 33-34 ; WO 2008/051477 A2
  • Route3
    • null|null
      50893-53-3
    • null|null
      1170994-04-3
    • ~90%
    • In-stock
      4-Bromoisoindoline hydrochloride|CS-W007793
      923590-95-8

    References

    • Song, Zhiguo J.; Tellers, David M.; Journet, Michel; Kuethe, Jeffrey T.; Lieberman, David; Humphrey, Guy; Zhang, Fei; Peng, Zhihui; Waters, Marjorie S.; Zewge, Daniel; Nolting, Andrew; Zhao, Dalian; Reamer, Robert A.; Dormer, Peter G.; Belyk, Kevin M.; Davies, Ian W.; Devine, Paul N.; Tschaen, David M. Journal of Organic Chemistry, 2011 , vol. 76, # 19 p. 7804 - 7815

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H411
Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P391-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.03
  • LogP   2.4741
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Bromoisoindoline hydrochloride sigma4-Bromoisoindoline hydrochloride manufacturer4-Bromoisoindoline hydrochloride price4-Bromoisoindoline hydrochloride structure4-Bromoisoindoline hydrochloride SDSbuy 4-Bromoisoindoline hydrochloride4-Bromoisoindoline hydrochloride supplier4-Bromoisoindoline hydrochloride uses4-Bromoisoindoline hydrochloride molecular weightprice of 4-Bromoisoindoline hydrochloride4-Bromoisoindoline hydrochloride chemical name formula of 4-Bromoisoindoline hydrochloride
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label