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CS-W001157 4
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Ethyl 3-ethoxy-2-propenoate

  • CAS No. 1001-26-9

  • Cat. No. CS-W002052
  • Purity≥97%
  • MDL No.MFCD00009863

*For research and further manufacturing use only, not for direct human use.

Ethyl 3-ethoxy-2-propenoate|CS-W002052

Structure of 1001-26-9

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General Information

  • CAS No. 1001-26-9
  • Cat. No. CS-W002052
  • Purity ≥97%
  • MDL No. MFCD00009863
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂O₃
  • Molecular Weight 144.17
  • Synonym(s) 3-Ethoxyacrylic Acid Ethyl Ester (cis- and trans- mixture)
  • SMILES CCOC=CC(=O)OCC

Description

Ethyl 3-ethoxy-2-propenoate is a reactive acrylate ester featuring a conjugated enoate system that facilitates efficient Michael additions and copolymerization. The ethoxy substituent enhances solubility in polar organic media while maintaining stability under standard bench conditions. This compound integrates readily into synthetic sequences requiring electrophilic alkene functionality.

Application

Ethyl 3-ethoxy-2-propenoate serves as a versatile Michael acceptor and enol ether building block in synthetic organic chemistry. Its conjugated ester-enol ether system enables reliable Diels-Alder cycloadditions, nucleophilic additions, and heterocycle formation under mild conditions. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and materials development.

Synthesis

  • Route1
    • null|null
      105-36-2
    • null|null
      122-51-0
    • ~%
    • In-stock
      Ethyl 3-ethoxy-2-propenoate|CS-W002052
      1001-26-9

    References

    • Journal of the American Chemical Society, , vol. 69, p. 2234
  • Route2
    • null|null
      64-17-5
    • null|null
      623-47-2
    • ~84%
    • In-stock
      Ethyl 3-ethoxy-2-propenoate|CS-W002052
      1001-26-9

    References

    • Anderson; Richardson Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 6 p. 1735 - 1737
  • Route3
    • null|null
      74-86-2
    • null|null
      105-58-8
    • ~%
    • In-stock
      Ethyl 3-ethoxy-2-propenoate|CS-W002052
      1001-26-9

    References

    • Journal of the American Chemical Society, , vol. 71, p. 1259

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: 3334
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   1.0997
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   4

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