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Structure of 918898-11-0
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5,7-Dichloropyrido[4,3-d]pyrimidin-4(3H)-one is a heterocyclic scaffold featuring two chlorine substituents at the 5 and 7 positions, enhancing electron deficiency and metabolic stability. This core integrates readily into kinase inhibitors and medicinal chemistry libraries, offering high reactivity in nucleophilic substitution and coupling reactions under mild conditions.
5,7-Dichloropyrido[4,3-d]pyrimidin-4(3H)-one serves as a versatile building block in medicinal chemistry, enabling the synthesis of purine analogs and kinase inhibitors. Its dichloro substitution pattern enhances electrophilic reactivity at C5 and C7, facilitating nucleophilic displacement and transition-metal-catalyzed coupling reactions. The pyrimidinone core provides excellent stability under standard bench conditions and tolerates a range of functional groups, simplifying purification and downstream derivatization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: