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CS-W001157 4
Total: USD 88.00

(4-Chloro-2-formylphenyl)boronic acid

  • CAS No. 913835-76-4

  • Cat. No. CS-W001001
  • Purity≥97%
  • MDL No.MFCD08689492

*For research and further manufacturing use only, not for direct human use.

(4-Chloro-2-formylphenyl)boronic acid|CS-W001001

Structure of 913835-76-4

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General Information

  • CAS No. 913835-76-4
  • Cat. No. CS-W001001
  • Purity ≥97%
  • MDL No. MFCD08689492
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BClO₃
  • Molecular Weight 184.38
  • Synonym(s) 4-Chloro-2-formylphenylboronic acid
  • SMILES OB(C1=CC=C(Cl)C=C1C=O)O

Description

This boronic acid features a chlorinated aryl ring with a formyl group at the para position relative to the boronate, enabling selective coupling in Suzuki-Miyaura reactions. The electron-withdrawing chlorine enhances electrophilicity of the adjacent carbonyl, facilitating downstream functionalization. Bench-stable under standard conditions, it integrates seamlessly into complex molecule synthesis workflows.

Application

(4-Chloro-2-formylphenyl)boronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The formyl group offers direct access to aldehyde functionality for downstream derivatization, while the boronic acid moiety ensures compatibility with Suzuki-Miyaura coupling protocols. Bench-stable and readily purified by recrystallization, it facilitates streamlined synthesis of complex aromatic systems relevant to pharmaceutical and agrochemical development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   -0.1677
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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