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CS-W001157 4
Total: USD 88.00

(3-Fluoro-2-formylphenyl)boronic acid

  • CAS No. 871126-15-7

  • Cat. No. CS-W000994
  • Purity≥98%
  • MDL No.MFCD10697421

*For research and further manufacturing use only, not for direct human use.

(3-Fluoro-2-formylphenyl)boronic acid|CS-W000994

Structure of 871126-15-7

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General Information

  • CAS No. 871126-15-7
  • Cat. No. CS-W000994
  • Purity ≥98%
  • MDL No. MFCD10697421
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BFO₃
  • Molecular Weight 167.93
  • Synonym(s) None
  • SMILES O=Cc1c(F)cccc1B(O)O

Description

This boronate moiety integrates a fluorinated aryl scaffold with a formyl group, enabling direct functionalization in cross-coupling and derivatization workflows. The ortho-fluoro substituent enhances electrophilicity while maintaining stability under standard conditions.

Application

(3-Fluoro-2-formylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-formyl group facilitates downstream transformations such as cyclizations and oxime formation, while the boronic acid moiety offers excellent stability and compatibility with diverse functional groups. Its bench-stable nature and predictable reactivity make it ideal for iterative synthesis workflows in medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   -0.682
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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