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CS-W001157 4
Total: USD 88.00

(2-Formyl-4-methoxyphenyl)boronic acid

  • CAS No. 139962-95-1

  • Cat. No. CS-0100651
  • Molecule weight179.97
  • Purity≥98%
  • MDL No.MFCD01319043

*For research and further manufacturing use only, not for direct human use.

(2-Formyl-4-methoxyphenyl)boronic acid|CS-0100651

Structure of 139962-95-1

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General Information

  • CAS No. 139962-95-1
  • Cat. No. CS-0100651
  • Purity ≥98%
  • MDL No. MFCD01319043
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BO₄
  • Molecular Weight 179.97
  • Synonym(s) 4-Methoxy-2-formylphenylboronic acid
  • SMILES OB(C1=CC=C(OC)C=C1C=O)O

Description

This boronic acid features a formyl group ortho to the boronate, enabling direct coupling in Suzuki-Miyaura reactions. The methoxy substituent enhances solubility and stabilizes the boron center under standard conditions. Designed for efficient integration into complex molecular architectures.

Synthesis

  • Route1
    • 2-(2-Bromo-5-methoxyphenyl)-1,3-dioxolane|CS-0193421
      98015-07-7
    • ~91%
    • In-stock
      (2-Formyl-4-methoxyphenyl)boronic acid|CS-0100651
      139962-95-1

    References

    • Kumar, Subodh Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1018 - 1023
  • Route2

    References

    • Tetrahedron Letters, , vol. 46, # 1 p. 139 - 142
  • Route3
    • 2-(2-Bromo-5-methoxyphenyl)-1,3-dioxane|CS-0746772
      1186304-21-1
    • ~50%
    • In-stock
      (2-Formyl-4-methoxyphenyl)boronic acid|CS-0100651
      139962-95-1

    References

    • Speicher, Andreas; Groh, Matthias; Hennrich, Markus; Huynh, Anh-Minh European Journal of Organic Chemistry, 2010 , # 35 p. 6760 - 6778

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.76
  • LogP   -0.8125
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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