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CS-W001157 4
Total: USD 88.00

(2-Formylthiophen-3-yl)boronic acid

  • CAS No. 4347-31-3

  • Cat. No. CS-0043939
  • Purity≥97%
  • MDL No.MFCD01075678

*For research and further manufacturing use only, not for direct human use.

(2-Formylthiophen-3-yl)boronic acid|CS-0043939

Structure of 4347-31-3

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General Information

  • CAS No. 4347-31-3
  • Cat. No. CS-0043939
  • Purity ≥97%
  • MDL No. MFCD01075678
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BO₃S
  • Molecular Weight 155.97
  • Synonym(s) 2-Formylthiophene-3-boronic acid
  • SMILES OB(O)C1=C(SC=C1)C=O

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering functionalized thiophene scaffolds with high efficiency. The aldehyde group enables downstream derivatization via condensation or reductive amination, enhancing synthetic versatility in pharmaceutical and materials chemistry applications.

Application

(2-Formylthiophen-3-yl)boronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biologically relevant thiophene-containing scaffolds. The pendant aldehyde group offers orthogonal functionality for downstream derivatization via reductive amination or condensation reactions. Its stability under standard reaction conditions and compatibility with common protecting groups facilitate streamlined synthesis in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   -0.7596
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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