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CS-W001157 4
Total: USD 88.00

1-Iodo-2-naphthol

  • CAS No. 2033-42-3

  • Cat. No. CS-W002225
  • Purity≥98%
  • MDL No.MFCD00046371

*For research and further manufacturing use only, not for direct human use.

1-Iodo-2-naphthol|CS-W002225

Structure of 2033-42-3

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General Information

  • CAS No. 2033-42-3
  • Cat. No. CS-W002225
  • Purity ≥98%
  • MDL No. MFCD00046371
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇IO
  • Molecular Weight 270.07
  • Synonym(s) 4-06-00-04305 (Beilstein Handbook Reference)
  • SMILES Oc1ccc2c(c1I)cccc2

Description

Janus Green B is a stain that interacts with DNA and has been used for histology studies including mitochondrial staining, in which its oxidation and reduction reveals alterations to the electron transfer chain. The stain has been utilized in studies for effective and rapid staining of insect chordotonal organs and peripheral nerves, where the nerves appear dark blue in comparison to non stained tissue. With the use of Janus Green B, rabbit lymphatic vessel studies demonstrate that threadlike structures within the lymphatic vessels, known as Bonghan ducts, contain a high density of mitochondria in their cells.

Application

1-Iodo-2-naphthol serves as a versatile building block in synthetic organic chemistry, enabling efficient iodine-directed functionalization of naphthalene scaffolds. Its reactivity facilitates palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura and Stille couplings, under standard conditions. The molecule exhibits bench stability and compatibility with common protecting groups, simplifying purification and integration into complex molecular architectures. Functions effectively in the synthesis of biaryl systems and advanced heterocyclic frameworks relevant to pharmaceutical and materials research.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   3.15
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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