5-Chloro-6-methoxy-1H-indole

Name: 5-Chloro-6-methoxy-1H-indole
Brand: ChemScene
Availability: OutOfStock
Rating: 5 (1 reviews)

CAS No. 90721-60-1
Cat. No. CS-0054215
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 90721-60-1

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Chloro-6-methoxy-1H-indole is a heterocyclic building block featuring a chlorinated and methoxylated indole core. This electron-deficient scaffold enables direct functionalization in C–H activation and cross-coupling processes. The methoxy group enhances solubility and modulates reactivity, while the chlorine serves as a handle for palladium-catalyzed transformations. Bench-stable under standard conditions, it integrates efficiently into pharmaceutical and agrochemical intermediates.

Application

5-Chloro-6-methoxy-1H-indole serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C5 and C6 positions. Its ortho-chloro and methoxy substituents provide complementary reactivity for palladium-catalyzed cross-coupling and electrophilic substitution, respectively. The compound exhibits good bench stability and facilitates efficient synthesis of indole-based pharmaceutical intermediates, particularly in kinase inhibitor and CNS-targeted scaffolds.

General Information

CAS No. 90721-60-1
Cat. No. CS-0054215
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₈ClNO
Molecular Weight 181.62
Synonym(s) 5-CHLORO-6-METHOXYINDOLE
SMILES COC1=CC2=C(C=C1Cl)C=CN2

Computational Chemistry Data

TPSA 25.02
LogP 2.8299
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Indole compounds

Key Words

5-Chloro-6-methoxy-1H-indole sigma5-Chloro-6-methoxy-1H-indole manufacturer5-Chloro-6-methoxy-1H-indole price5-Chloro-6-methoxy-1H-indole structure5-Chloro-6-methoxy-1H-indole SDSbuy 5-Chloro-6-methoxy-1H-indole5-Chloro-6-methoxy-1H-indole supplier5-Chloro-6-methoxy-1H-indole uses5-Chloro-6-methoxy-1H-indole molecular weightprice of 5-Chloro-6-methoxy-1H-indole5-Chloro-6-methoxy-1H-indole chemical name formula of 5-Chloro-6-methoxy-1H-indole

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Chloro-6-methoxy-1H-indole

CAS No. 90721-60-1

Recommended Products