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CS-W001157 4
Total: USD 88.00

2-(Methylamino)benzaldehyde

  • CAS No. 7755-70-6

  • Cat. No. CS-W021444
  • Purity≥97%
  • MDL No.MFCD19216814

*For research and further manufacturing use only, not for direct human use.

2-(Methylamino)benzaldehyde|CS-W021444

Structure of 7755-70-6

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General Information

  • CAS No. 7755-70-6
  • Cat. No. CS-W021444
  • Purity ≥97%
  • MDL No. MFCD19216814
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO
  • Molecular Weight 135.16
  • Synonym(s) None
  • SMILES O=CC1=CC=CC=C1NC

Description

2-(Methylamino)benzaldehyde features a para-substituted benzaldehyde core bearing a methylamino group, enabling facile integration into Schiff base formations and heterocyclic syntheses. This electron-rich aromatic aldehyde exhibits enhanced solubility in polar organic solvents and maintains stability under standard bench conditions, making it well-suited for use in medicinal chemistry and ligand development workflows.

Application

2-(Methylamino)benzaldehyde serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to biologically relevant scaffolds. Its ortho-aminoaldehyde functionality facilitates straightforward imine formation, cyclizations, and transition-metal-catalyzed coupling reactions. The molecule exhibits good bench stability and is readily purified by recrystallization or column chromatography, making it suitable for scale-up and multi-step synthetic sequences.

Synthesis

  • Route1
    • In-stock
      Benzo[c]isoxazole|CS-0143974
      271-58-9
    • null|null
      917-54-4
    • ~90%
    • In-stock
      2-(Methylamino)benzaldehyde|CS-W021444
      7755-70-6

    References

    • Heaney, Frances; McCarthy, Tomas; Mahon, Mary; McKee Organic and Biomolecular Chemistry, 2005 , vol. 3, # 24 p. 4351 - 4361
  • Route2

    References

    • Lee, Yong Rok; Hung, Thai Viet Tetrahedron, 2008 , vol. 64, # 30-31 p. 7338 - 7346
  • Route3
    • null|null
      71492-76-7
    • ~%
    • In-stock
      2-(Methylamino)benzaldehyde|CS-W021444
      7755-70-6

    References

    • Sisko, Joseph; Weinreb, Steven M. Synthetic Communications, 1988 , vol. 18, # 10 p. 1035 - 1042

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.5408
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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