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Structure of 903895-48-7
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tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate delivers a boronate ester functionality paired with a tert-butyl carboxylate handle, enabling efficient Suzuki-Miyaura coupling under mild conditions. The tetramethyl-substituted dioxaborolane ring ensures excellent stability and compatibility with diverse reaction environments. This robust reagent integrates seamlessly into synthetic sequences requiring orthogonal functionalization.
tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The sterically protected boronate ester exhibits excellent functional group tolerance and facilitates efficient C–C bond formation with aryl halides and triflates under mild conditions. Its tert-butyl ester moiety enables straightforward deprotection to the corresponding carboxylic acid, providing direct access to key intermediates in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: