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CS-W001157 4
Total: USD 88.00

3-Carboxyphenylboronic acid pinacol ester

  • CAS No. 269409-73-6

  • Cat. No. CS-W003049
  • Purity≥98%
  • MDL No.MFCD03411930

*For research and further manufacturing use only, not for direct human use.

3-Carboxyphenylboronic acid pinacol ester|CS-W003049

Structure of 269409-73-6

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General Information

  • CAS No. 269409-73-6
  • Cat. No. CS-W003049
  • Purity ≥98%
  • MDL No. MFCD03411930
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₇BO₄
  • Molecular Weight 248.08
  • Synonym(s) None
  • SMILES O=C(O)C1=CC(B2OC(C)(C)C(C)(C)O2)=CC=C1

Description

3-Carboxyphenylboronic acid pinacol ester features a boronate ester moiety that enhances stability and solubility in aqueous and organic media. This bench-stable derivative enables efficient Suzuki-Miyaura coupling reactions under standard conditions, facilitating the construction of biaryl architectures in synthetic and medicinal chemistry workflows.

Application

3-Carboxyphenylboronic acid pinacol ester serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. Its pinacol boronate ester functionality enables reliable coupling with aryl and vinyl halides under mild conditions, while the pendant carboxylic acid group offers direct access to functionalized arenes for pharmaceutical and materials applications. The ester protects the boronic acid during storage and handling, facilitating purification and compatibility with diverse reaction matrices.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   1.684
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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