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CS-W001157 4
Total: USD 88.00

5-Cyclopropyl-1,3,4-oxadiazol-2-amine

  • CAS No. 89179-60-2

  • Cat. No. CS-W011175
  • Purity≥97%
  • MDL No.MFCD09041179

*For research and further manufacturing use only, not for direct human use.

5-Cyclopropyl-1,3,4-oxadiazol-2-amine|CS-W011175

Structure of 89179-60-2

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General Information

  • CAS No. 89179-60-2
  • Cat. No. CS-W011175
  • Purity ≥97%
  • MDL No. MFCD09041179
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇N₃O
  • Molecular Weight 125.13
  • Synonym(s) 1,3,4-Oxadiazol-2-amine,5-cyclopropyl
  • SMILES NC1=NN=C(C2CC2)O1

Description

5-Cyclopropyl-1,3,4-oxadiazol-2-amine delivers a rigid, electron-rich heterocyclic core ideal for bioactive molecule design. This bench-stable scaffold integrates readily into pharmaceutical candidates, offering enhanced metabolic resistance and favorable solubility profiles in polar solvents.

Application

5-Cyclopropyl-1,3,4-oxadiazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through reliable functional group transformations. Its stability under standard reaction conditions and tolerance to diverse functional groups facilitate efficient synthesis of oxadiazole-containing APIs. The cyclopropyl substituent enhances metabolic stability and modulates lipophilicity, supporting optimized pharmacokinetic profiles.

Synthesis

  • Route1
    • In-stock
      Cyclopropanecarbohydrazide|CS-D0255
      6952-93-8
    • null|null
      506-68-3
    • ~%
    • In-stock
      5-Cyclopropyl-1,3,4-oxadiazol-2-amine|CS-W011175
      89179-60-2

    References

    • Journal of Medicinal and Pharmaceutical Chemistry, , vol. 5, p. 617 - 626

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.94
  • LogP   0.5292
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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