6-Chloro-2-methylnicotinaldehyde

Name: 6-Chloro-2-methylnicotinaldehyde
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 884495-36-7
Cat. No. CS-0036209
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Chloro-2-methylnicotinaldehyde|CS-0036209

Structure of 884495-36-7

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 884495-36-7
Cat. No. CS-0036209
Purity ≥98%
MDL No. None
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆ClNO
Molecular Weight 155.58
Synonym(s) 6-Chloro-3-formyl-2-picoline
SMILES CC1=NC(=CC=C1C=O)Cl

Description

6-Chloro-2-methylnicotinaldehyde features a chlorine-substituted pyridine ring with a methylene group at the 2-position and an aldehyde functionality at the 6-position. This electron-deficient heterocyclic scaffold integrates readily into synthetic routes for bioactive molecules, offering enhanced reactivity in coupling and condensation reactions under standard conditions.

Application

6-Chloro-2-methylnicotinaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted pyridine and nicotinamide derivatives. Its aldehyde functionality facilitates reductive amination, condensation, and coupling reactions, while the 6-chloro and 2-methyl substituents provide orthogonal reactivity and steric modulation. The compound exhibits good bench stability and is compatible with standard purification protocols, making it suitable for scale-up and multi-step synthesis workflows.

Synthesis

Route1
- In-stock
  
  132606-40-7
- 68-12-2
- ~69%
- In-stock
  
  884495-36-7
References
- ANORMED INC. Patent: WO2007/22371 A2, 2007 ; Location in patent: Page/Page column 50 ; WO 2007/022371 A2
Route2
- In-stock
  
  66909-36-2
- ~%
- In-stock
  
  884495-36-7
References
- WO2009/58923 A1, ; Page/Page column 16 ; WO 2009/058923 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 29.96
LogP 1.85592
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Aldehyde

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

6-Chloro-2-methylnicotinaldehyde sigma6-Chloro-2-methylnicotinaldehyde manufacturer6-Chloro-2-methylnicotinaldehyde price6-Chloro-2-methylnicotinaldehyde structure6-Chloro-2-methylnicotinaldehyde SDSbuy 6-Chloro-2-methylnicotinaldehyde6-Chloro-2-methylnicotinaldehyde supplier6-Chloro-2-methylnicotinaldehyde uses6-Chloro-2-methylnicotinaldehyde molecular weightprice of 6-Chloro-2-methylnicotinaldehyde6-Chloro-2-methylnicotinaldehyde chemical name formula of 6-Chloro-2-methylnicotinaldehyde

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Chloro-2-methylnicotinaldehyde

CAS No. 884495-36-7

Recommended Products