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CS-W001157 4
Total: USD 88.00

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester

  • CAS No. 170848-34-7

  • Cat. No. CS-Z0021
  • Molecule weight329.13
  • Purity≥97%
  • MDL No.MFCD00216580

*For research and further manufacturing use only, not for direct human use.

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester|CS-Z0021

Structure of 170848-34-7

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General Information

  • CAS No. 170848-34-7
  • Cat. No. CS-Z0021
  • Purity ≥97%
  • MDL No. MFCD00216580
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆INO₄
  • Molecular Weight 329.13
  • Synonym(s) Methyl (2S)-2-(tert-butoxycarbonylamino)-3-iodopropanoate; Methyl (S)-2-[(tert-butoxycarbonyl)amino]-3-iodopropanoate
  • SMILES O=C(OC)[C@@H](CI)NC(OC(C)(C)C)=O

Description

This chiral building block features a protected amino group and a reactive iodopropionic ester moiety, enabling selective conjugation in peptide synthesis. The tert-butyl carbamate handle ensures stability during purification, while the methyl ester facilitates downstream transformations.

Application

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester serves as a versatile chiral building block for the synthesis of β-amino acids and peptidomimetics. The iodide functionality enables palladium-catalyzed cross-coupling reactions, while the Boc-protected amine and ester groups offer orthogonal handling and compatibility with standard peptide synthesis workflows. Bench-stable and readily purified by flash chromatography, it facilitates efficient access to biologically relevant scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.63
  • LogP   1.4877
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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