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Structure of 882679-08-5
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This boronate-functional aniline integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, offering enhanced stability and compatibility under standard conditions. The para-trifluoromethyl group imparts electron-withdrawing character, while the tetramethyl-dioxaborolane moiety ensures reliable coupling efficiency. Designed for robust performance in complex synthesis workflows.
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)aniline serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables reliable coupling with aryl and heteroaryl halides under mild conditions, while the para-trifluoromethyl aniline scaffold provides enhanced metabolic stability and lipophilicity—key attributes in medicinal chemistry. Bench-stable and readily purified by flash chromatography, it facilitates efficient construction of complex biaryl architectures relevant to pharmaceutical and agrochemical discovery.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: