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CS-W001157 4
Total: USD 88.00

4-Aminopentanoic acid

  • CAS No. 13880-74-5

  • Cat. No. CS-0276521
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Aminopentanoic acid|CS-0276521

Structure of 13880-74-5

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General Information

  • CAS No. 13880-74-5
  • Cat. No. CS-0276521
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO₂
  • Molecular Weight 117.15
  • Synonym(s) rac 4-Aminopentanoic acid
  • SMILES CC(N)CCC(O)=O

Description

4-Aminopentanoic acid is a linear aliphatic amino acid featuring an amine group at the C4 position and a carboxylic acid terminus. This structure enables direct incorporation into peptide chains or conjugation strategies requiring a flexible, hydrophilic spacer. The molecule exhibits enhanced solubility in aqueous buffers and stability under standard bench conditions, facilitating use in synthetic biology and chemical biology workflows.

Application

4-Aminopentanoic acid serves as a versatile building block in peptide synthesis and medicinal chemistry, offering a linear aliphatic chain with complementary amine and carboxylic acid functional groups. Its well-defined reactivity enables straightforward coupling reactions, side-chain derivatization, and incorporation into bioactive scaffolds. The molecule exhibits good bench stability and facilitates purification via standard ion-exchange or crystallization techniques, making it suitable for both small-scale research and process development applications.

Synthesis

  • Route1
    • null|null
      108-27-0
    • ~91%
    • In-stock
      4-Aminopentanoic acid|CS-0276521
      13880-74-5

    References

    • Elz, Sigurd; Schunack, Walter Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1987 , vol. 42, # 2 p. 238 - 242
  • Route2
    • null|null
      1258963-02-8
    • ~97%
    • In-stock
      4-Aminopentanoic acid|CS-0276521
      13880-74-5

    References

    • Gracia, Stephanie; Jerpan, Rudolf; Pellet-Rostaing, Stephane; Popowycz, Florence; Lemaire, Marc Tetrahedron Letters, 2010 , vol. 51, # 48 p. 6290 - 6293
  • Route3
    • 4-(Phenylhydrazono)Pentanoic acid|CS-0766047
      588-60-3
    • ~%
    • In-stock
      4-Aminopentanoic acid|CS-0276521
      13880-74-5

    References

    • Tafel Chemische Berichte, 1886 , vol. 19, p. 2416 Chemische Berichte, 1889 , vol. 22, p. 1862

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.1984
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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