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Structure of 1259285-61-4
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This boronate-functionalized aniline integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, offering enhanced stability and reactivity under standard conditions. The trifluoromethyl group imparts electron-withdrawing character and improved metabolic resistance, while the tetramethylborolane moiety ensures bench-stable handling and high functional group tolerance.
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)aniline serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the pinacol boronate moiety ensures excellent bench stability and compatibility with diverse reaction conditions. This compound facilitates efficient construction of biaryl scaffolds in medicinal chemistry and materials science, enabling rapid access to functionalized heterocycles and advanced intermediates under mild, catalytic conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: