Methyl 6-chloro-2-methylnicotinate

Name: Methyl 6-chloro-2-methylnicotinate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 851759-19-8
Cat. No. CS-0139259
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 6-chloro-2-methylnicotinate|CS-0139259

Structure of 851759-19-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Methyl 6-chloro-2-methylnicotinate is a halogenated pyridine ester featuring a chlorinated C6 position and a methyl-substituted C2 carbon. This electron-deficient heterocycle integrates readily into synthetic sequences requiring steric bulk and polarized ring systems. The methyl ester group enables direct derivatization or hydrolysis to the corresponding acid, facilitating downstream functionalization in medicinal chemistry and agrochemical development under standard conditions.

Application

Methyl 6-chloro-2-methylnicotinate serves as a versatile building block in the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-substituted pyridine core enables directed functionalization, while the methyl ester group facilitates selective transformations. The 6-chloro substituent provides a handle for palladium-catalyzed cross-coupling reactions, and the 2-methyl group enhances stability and influences regioselectivity. This compound exhibits excellent bench stability and is compatible with standard purification methods, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

General Information

CAS No. 851759-19-8
Cat. No. CS-0139259
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈ClNO₂
Molecular Weight 185.61
Synonym(s) Methyl 6-chloro-2-methylpyridine-3-carboxylate
SMILES O=C(C1=CC=C(Cl)N=C1C)OC

Computational Chemistry Data

TPSA 39.19
LogP 1.83002
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

Methyl 6-chloro-2-methylnicotinate sigmaMethyl 6-chloro-2-methylnicotinate manufacturerMethyl 6-chloro-2-methylnicotinate priceMethyl 6-chloro-2-methylnicotinate structureMethyl 6-chloro-2-methylnicotinate SDSbuy Methyl 6-chloro-2-methylnicotinateMethyl 6-chloro-2-methylnicotinate supplierMethyl 6-chloro-2-methylnicotinate usesMethyl 6-chloro-2-methylnicotinate molecular weightprice of Methyl 6-chloro-2-methylnicotinateMethyl 6-chloro-2-methylnicotinate chemical name formula of Methyl 6-chloro-2-methylnicotinate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 6-chloro-2-methylnicotinate

CAS No. 851759-19-8

Recommended Products