Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(2,6-dichloro-3-methoxyphenyl)boronic acid

  • CAS No. 851756-57-5

  • Cat. No. CS-0035804
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2,6-dichloro-3-methoxyphenyl)boronic acid|CS-0035804

Structure of 851756-57-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 851756-57-5
  • Cat. No. CS-0035804
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BCl₂O₃
  • Molecular Weight 220.85
  • Synonym(s) 2,6-dichloro-3-Methoxyphenylboronic acid
  • SMILES COC1=CC=C(C(=C1Cl)B(O)O)Cl

Description

This boronic acid features a methoxy-substituted aryl ring flanked by two chlorine atoms at the 2 and 6 positions, delivering enhanced stability and predictable reactivity in Suzuki-Miyaura coupling. The electron-withdrawing chlorines modulate nucleophilicity while the methoxy group improves solubility and facilitates downstream functionalization.

Application

(2,6-dichloro-3-methoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its stability under ambient conditions and tolerance to various functional groups facilitate straightforward purification and integration into complex molecular architectures. The dichloro substitution pattern enhances electrophilic reactivity in downstream transformations, while the methoxy group provides directional control in regioselective coupling processes.

Synthesis

  • Route1

    References

    • TargeGen, Inc. Patent: US2005/245524 A1, 2005 ; Location in patent: Page/Page column 102 ; US 20050245524 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   49.69
  • LogP   0.6818
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 851756-57-5 sigma851756-57-5 manufacturer851756-57-5 price851756-57-5 structure851756-57-5 SDSbuy 851756-57-5851756-57-5 supplier851756-57-5 uses851756-57-5 molecular weightprice of 851756-57-5851756-57-5 chemical name formula of 851756-57-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label