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CS-W001157 4
Total: USD 88.00

4-Bromo-6-iodo-1H-indole

  • CAS No. 850334-30-4

  • Cat. No. CS-0163676
  • Molecule weightNone
  • Purity≥98%
  • MDL No.MFCD07781510

*For research and further manufacturing use only, not for direct human use.

4-Bromo-6-iodo-1H-indole|CS-0163676

Structure of 850334-30-4

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General Information

  • CAS No. 850334-30-4
  • Cat. No. CS-0163676
  • Purity ≥98%
  • MDL No. MFCD07781510
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrIN
  • Molecular Weight None
  • Synonym(s) 4-Bromo-6-iodo indole
  • SMILES IC1=CC2=C(C(Br)=C1)C=CN2

Description

4-Bromo-6-iodo-1H-indole features a uniquely functionalized indole core with bromo and iodo substituents at the 4- and 6-positions, respectively. This electron-deficient scaffold enables direct cross-coupling reactions under palladium catalysis, facilitating rapid access to complex heterocyclic architectures in medicinal chemistry and materials science. The molecule exhibits enhanced stability and predictable reactivity in standard synthetic workflows.

Application

4-Bromo-6-iodo-1H-indole serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling the construction of biologically relevant indole scaffolds. Its complementary halogenation pattern supports sequential functionalization via orthogonal C–H activation or Suzuki-Miyaura coupling protocols. The molecule exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for medicinal chemistry campaigns and process-scale synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   15.79
  • LogP   3.535
  • H_Acceptors   0
  • H_Donors   1
  • Rotatable_Bonds   0

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