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Structure of 134872-23-4
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2-Bromo-5-(methylthio)pyridine is a versatile heterocyclic building block featuring a bromine atom at the 2-position and a methylthio group at the 5-position on the pyridine ring. This combination enables direct functionalization in cross-coupling reactions, particularly Suzuki-Miyaura and Stille couplings, due to the reactive halogen and electron-donating sulfur substituent. The molecule exhibits excellent stability under standard bench conditions and integrates readily into complex molecular architectures for pharmaceutical and agrochemical synthesis.
2-Bromo-5-(methylthio)pyridine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromide and compatible methylthio group. The molecule exhibits good bench stability and facilitates the construction of complex pyridine-based scaffolds commonly found in pharmaceutical intermediates. Its functional group tolerance supports diverse transformations in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: