2-(6-Hydroxy-[1,1'-biphenyl]-3-carbonyl)benzoic acid

Name: 2-(6-Hydroxy-[1,1'-biphenyl]-3-carbonyl)benzoic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 84627-04-3
Cat. No. CS-0468443
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(6-Hydroxy-[1,1'-biphenyl]-3-carbonyl)benzoic acid|CS-0468443

Structure of 84627-04-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 84627-04-3
Cat. No. CS-0468443
Purity ≥98%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₀H₁₄O₄
Molecular Weight 318.32
Synonym(s) Fendizoic acid
SMILES O=C(O)C1=CC=CC=C1C(C2=CC(C3=CC=CC=C3)=C(O)C=C2)=O

Description

This biphenyl-based carboxylic acid features a hydroxyl group at the 6-position of the phenyl ring, enhancing solubility and enabling hydrogen bonding. The para-substituted benzoic acid moiety provides a rigid, electron-deficient platform ideal for conjugate addition reactions and molecular scaffold integration in medicinal chemistry.

Application

2-(6-Hydroxy-[1,1'-biphenyl]-3-carbonyl)benzoic acid serves as a versatile building block for constructing biaryl-containing scaffolds in medicinal chemistry and materials science. The molecule combines a carboxylic acid functionality with a phenolic hydroxyl group, enabling diverse derivatization via amide, ester, or ether formation. Its biphenyl core offers structural rigidity and π-conjugation, while the ortho-carbonyl substitution pattern supports controlled reactivity in coupling and cyclization reactions. This compound demonstrates bench stability and compatibility with standard purification methods, facilitating integration into multi-step synthetic sequences.

Synthesis

Route1
- 85-44-9
- 90-43-7
- ~42%
- In-stock
  
  84627-04-3
References
- Polish Journal of Chemistry, , vol. 55, # 5 p. 995 - 1005

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H319-H412
Precautionary Statements : P264-P270-P273-P280-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 74.6
LogP 3.9884
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 4

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Ketone

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

84627-04-3 sigma84627-04-3 manufacturer84627-04-3 price84627-04-3 structure84627-04-3 SDSbuy 84627-04-384627-04-3 supplier84627-04-3 uses84627-04-3 molecular weightprice of 84627-04-384627-04-3 chemical name formula of 84627-04-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-(6-Hydroxy-[1,1'-biphenyl]-3-carbonyl)benzoic acid

CAS No. 84627-04-3

Recommended Products