7-Bromoimidazo[1,2-a]pyridine

Name: 7-Bromoimidazo[1,2-a]pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 808744-34-5
Cat. No. CS-W008842
Purity≥95%
MDL No.MFCD07778353

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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7-Bromoimidazo[1,2-a]pyridine|CS-W008842

Structure of 808744-34-5

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General Information

CAS No. 808744-34-5
Cat. No. CS-W008842
Purity ≥95%
MDL No. MFCD07778353
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅BrN₂
Molecular Weight 197.03
Synonym(s) Imidazo[1,2-a]pyridine, 7-bromo-
SMILES BrC1=CC2=NC=CN2C=C1

Description

7-Bromoimidazo[1,2-a]pyridine is a bench-stable heterocyclic scaffold featuring a bromine substituent at the 7-position, enabling direct functionalization in cross-coupling reactions. This electron-deficient imidazopyridine integrates readily into pharmaceutical intermediates and materials chemistry, offering enhanced reactivity and structural rigidity for targeted molecular design.

Application

7-Bromoimidazo[1,2-a]pyridine serves as a versatile building block for heterocyclic synthesis, enabling efficient access to biologically relevant scaffolds through palladium-catalyzed cross-coupling reactions. Its bromine substituent facilitates reliable functionalization under standard conditions, while the imidazopyridine core offers favorable stability and compatibility with diverse reaction environments. This compound is particularly valuable in medicinal chemistry for constructing kinase inhibitors and other targeted therapeutics.

Synthesis

Route1
- 107-20-0
- In-stock
  
  84249-14-9
- ~71%
- In-stock
  
  808744-34-5
References
- ARRAY BIOPHARMA INC. Patent: WO2008/124323 A1, 2008 ; Location in patent: Page/Page column 68 ; WO 2008/124323 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 17.3
LogP 2.0968
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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7-Bromoimidazo[1,2-a]pyridine

CAS No. 808744-34-5

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