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CS-W001157 4
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2-Methyl-6,7-dihydro-5h-pyrrolo[3,4-d]pyrimidine

  • CAS No. 787541-88-2

  • Cat. No. CS-0282427
  • Purity≥95%
  • MDL No.MFCD08447400

*For research and further manufacturing use only, not for direct human use.

2-Methyl-6,7-dihydro-5h-pyrrolo[3,4-d]pyrimidine|CS-0282427

Structure of 787541-88-2

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General Information

  • CAS No. 787541-88-2
  • Cat. No. CS-0282427
  • Purity ≥95%
  • MDL No. MFCD08447400
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉N₃
  • Molecular Weight 135.17
  • Synonym(s) None
  • SMILES CC1=NC2=C(CNC2)C=N1

Description

2-Methyl-6,7-dihydro-5h-pyrrolo[3,4-d]pyrimidine is a heterocyclic scaffold featuring a partially saturated pyrrolopyrimidine core with a methyl substituent at the 2-position. This structure provides a stable, electron-rich platform for medicinal chemistry applications. The compound exhibits favorable solubility and handling characteristics under standard bench conditions, enabling straightforward integration into synthetic sequences.

Application

2-Methyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its saturated pyrrolidine ring enables selective functionalization at the 5-position, while the fused pyrimidine core offers enhanced stability and predictable reactivity in cross-coupling and electrophilic substitution reactions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis of kinase inhibitors and other bioactive scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.81
  • LogP   0.38822
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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