Fmoc-Lys(Fmoc)-OH

Name: Fmoc-Lys(Fmoc)-OH
Brand: ChemScene
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CAS No. 78081-87-5
Cat. No. CS-W008386
Purity≥97%
MDL No.MFCD00080275

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 78081-87-5
Cat. No. CS-W008386
Purity ≥97%
MDL No. MFCD00080275
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₆H₃₄N₂O₆
Molecular Weight 590.66
Synonym(s) None
SMILES O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCCC[C@@H](C(O)=O)NC(OCC4C5=C(C6=C4C=CC=C6)C=CC=C5)=O

Description

Fmoc-Lys(Fmoc)-OH is a bifunctional amino acid derivative featuring two Fmoc groups flanking a lysine backbone, enabling efficient incorporation into solid-phase peptide synthesis. The dual protecting groups provide orthogonal deprotection capability, simplifying the construction of complex peptides with multiple lysine residues. This variant offers enhanced solubility and stability under standard bench conditions.

Application

Fmoc-Lys(Fmoc)-OH serves as a key building block in peptide synthesis, enabling the incorporation of lysine residues with orthogonal protection. The Fmoc group on the α-amino terminus allows for mild base-labile deprotection, while the side-chain Boc-like Fmoc protection ensures selective functionalization. This dual protection facilitates efficient coupling and stepwise assembly of complex peptides, offering excellent stability and ease of purification in solid-phase workflows.

Safety Information

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Signal Word : N/A	UN#: N/A
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Precautionary Statements : N/A

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Computational Chemistry Data

TPSA 113.96
LogP 6.6873
H_Acceptors 5
H_Donors 3
Rotatable_Bonds 11

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Lysine and derivatives

Building Blocks Functional Group Fmoc

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Fmoc-Lys(Fmoc)-OH

CAS No. 78081-87-5

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