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CS-W001157 4
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Boc-Thr-OH

  • CAS No. 2592-18-9

  • Cat. No. CS-W013153
  • Purity≥95%
  • MDL No.MFCD00065946

*For research and further manufacturing use only, not for direct human use.

Boc-Thr-OH|CS-W013153

Structure of 2592-18-9

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General Information

  • CAS No. 2592-18-9
  • Cat. No. CS-W013153
  • Purity ≥95%
  • MDL No. MFCD00065946
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇NO₅
  • Molecular Weight 219.23
  • Synonym(s) None
  • SMILES C[C@@H](O)[C@@H](C(O)=O)NC(OC(C)(C)C)=O

Description

Boc-Thr-OH serves as a key protected amino acid building block in peptide synthesis, featuring a stable tert-butoxycarbonyl group that enables selective coupling under standard conditions. The hydroxyl functionality allows for further derivatization while maintaining compatibility with common deprotection protocols.

Synthesis

  • Route1

    References

    • PFIZER INC.; BAGAL, Sharanjeet Kaur; BROWN, Alan Daniel; KEMP, Mark Ian; KLUTE, Wolfgang; MARRON, Brian Edward; MILLER, Duncan Charles; SKERRATT, Sarah Elizabeth; SUTO, Mark J.; WEST, Christopher William; MALET SANZ, Laia Patent: WO2013/114250 A1, 2013 ; Location in patent: Page/Page column 161; 162 ;
  • Route2

    References

    • Babu, S.N. Narendra; Srinivasa; Santhosh; Gowda, D. Channe Journal of Chemical Research, 2004 , # 1 p. 66 - 67
  • Route3
    • null|null
      77313-56-5
    • ~89%
    • In-stock
      Boc-Thr-OH|CS-W013153
      2592-18-9

    References

    • Namikoshi, Michio; Kundu, Bijoy; Rinehart, Kenneth L. Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5464 - 5466

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   95.86
  • LogP   0.3451
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   3

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