N-Methyl-L-threonine

Name: N-Methyl-L-threonine
Brand: ChemScene
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CAS No. 2812-28-4
Cat. No. CS-W011082
Purity≥97%
MDL No.MFCD02094308

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 2812-28-4

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General Information

CAS No. 2812-28-4
Cat. No. CS-W011082
Purity ≥97%
MDL No. MFCD02094308
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₁NO₃
Molecular Weight 133.15
Synonym(s) None
SMILES C[C@@H](O)[C@@H](C(O)=O)NC

Description

N-Methyl-L-threonine is a non-proteinogenic amino acid featuring a methylated amine group and two hydroxyl-bearing stereocenters. This configuration imparts enhanced metabolic stability and improved membrane permeability compared to its parent compound. The molecule integrates readily into peptide sequences, where the N-methyl substitution reduces backbone hydrogen bonding capacity and minimizes proteolytic degradation. Its steric bulk and polar functional groups enable fine-tuned solubility profiles in aqueous and organic media, facilitating use in synthetic peptide libraries and drug discovery campaigns.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 69.56
LogP -0.9602
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 3

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Threonine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids Biologically-modified Amino Acids

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N-Methyl-L-threonine

CAS No. 2812-28-4

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