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CS-W001157 4
Total: USD 88.00

trans-4-[[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]methyl]cyclohexanecarboxylic acid

  • CAS No. 167690-53-1

  • Cat. No. CS-0067149
  • Purity≥97%
  • MDL No.MFCD00273480

*For research and further manufacturing use only, not for direct human use.

trans-4-[[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]methyl]cyclohexanecarboxylic acid|CS-0067149

Structure of 167690-53-1

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General Information

  • CAS No. 167690-53-1
  • Cat. No. CS-0067149
  • Purity ≥97%
  • MDL No. MFCD00273480
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₅NO₄
  • Molecular Weight 379.45
  • Synonym(s) trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic Acid
  • SMILES O=C([C@H]1CC[C@H](CNC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)CC1)O

Description

trans-4-[[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]methyl]cyclohexanecarboxylic acid is a bench-stable, moisture-tolerant amino acid derivative featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group. This sterically hindered cyclohexane scaffold enables efficient incorporation into peptide synthesis workflows, offering high coupling fidelity and clean deprotection under standard conditions.

Synthesis

  • Route1
    • trans-4-(Aminomethyl)cyclohexanecarboxylic acid|CS-0655397
      1197-18-8
    • In-stock
      Fmoc-Osu Amino acid impurity|CS-1733136
      82911-69-1
    • ~95%
    • In-stock
      trans-4-[[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]methyl]cyclohexanecarboxylic acid|CS-0067149
      167690-53-1

    References

    • Dener, Jeffrey M.; Fantauzzi, Pascal P.; Kshirsagar, Tushar A.; Kelly, Daphne E.; Wolfe, Aaron B. Organic Process Research and Development, 2001 , vol. 5, # 4 p. 445 - 449

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.4161
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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