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CS-W001157 4
Total: USD 88.00

Mal-PEG1-acid

  • CAS No. 760952-64-5

  • Cat. No. CS-0108926
  • Purity≥96%
  • MDL No.MFCD24497443

*For research and further manufacturing use only, not for direct human use.

Mal-PEG1-acid|CS-0108926

Structure of 760952-64-5

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General Information

  • CAS No. 760952-64-5
  • Cat. No. CS-0108926
  • Purity ≥96%
  • MDL No. MFCD24497443
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₅
  • Molecular Weight 213.19
  • Synonym(s) None
  • SMILES O=C(O)CCOCCN1C(C=CC1=O)=O

Description

Mal-PEG1-acid is a maleimide-functionalized PEG linker bearing a terminal carboxylic acid group. This bifunctional architecture enables site-specific conjugation to thiol-containing biomolecules, followed by facile coupling to amine-presenting surfaces or reagents via standard carbodiimide chemistry. The short PEG spacer provides minimal steric hindrance while enhancing solubility in aqueous systems.

Application

Mal-PEG1-acid serves as a versatile bifunctional linker enabling site-specific conjugation via maleimide-thiol chemistry and providing a terminal carboxylic acid for amide coupling. Its short PEG spacer enhances solubility and reduces steric hindrance, while the stable maleimide group facilitates efficient bioconjugation under physiological conditions. Ideal for antibody-drug conjugates, peptide modifications, and surface functionalization, it offers reliable performance in diverse synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   83.91
  • LogP   -0.5973
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   6

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