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CS-W001157 4
Total: USD 88.00

m-PEG8-NHS ester

  • CAS No. 756525-90-3

  • Cat. No. CS-0031584
  • Purity≥98%
  • MDL No.MFCD13184969
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

m-PEG8-NHS ester|CS-0031584

Structure of 756525-90-3

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Description

m-PEG8-NHS ester enables efficient conjugation in aqueous media, combining the stability of a bench-stable NHS ester with the solubility and biocompatibility of a PEG8 spacer. This reagent facilitates site-specific labeling of primary amines in peptides, proteins, and biomolecules, streamlining bioconjugation workflows without compromising functional group integrity.

Application

m-PEG8-NHS ester serves as a versatile, water-soluble coupling reagent for amine functionalization in bioconjugation and polymer chemistry. Its eight-ethylene glycol spacer provides enhanced solubility and reduced non-specific binding, while the NHS ester group enables efficient reaction with primary amines under physiological conditions. Ideal for labeling proteins, peptides, and oligonucleotides, it offers excellent stability, ease of purification, and compatibility with standard synthetic workflows.

General Information

  • CAS No. 756525-90-3
  • Cat. No. CS-0031584
  • Purity ≥98%
  • MDL No. MFCD13184969
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₃₉NO₁₂
  • Molecular Weight 509.54
  • Synonym(s) None
  • SMILES COCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O

Computational Chemistry Data

  • TPSA   137.52
  • LogP   -0.2537
  • H_Acceptors   12
  • H_Donors   0
  • Rotatable_Bonds   25

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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