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CS-W001157 4
Total: USD 88.00

2H-1,2,3-Triazole

  • CAS No. 288-35-7

  • Cat. No. CS-0145707
  • Purity≥98%
  • MDL No.MFCD00962232

*For research and further manufacturing use only, not for direct human use.

2H-1,2,3-Triazole|CS-0145707

Structure of 288-35-7

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General Information

  • CAS No. 288-35-7
  • Cat. No. CS-0145707
  • Purity ≥98%
  • MDL No. MFCD00962232
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₃N₃
  • Molecular Weight 69.07
  • Synonym(s) 1H-1,2,3-Triazole
  • SMILES N1=CC=NN1

Description

2H-1,2,3-Triazole is a stable, heterocyclic nitrogen-rich compound featuring a fused five-membered ring with three nitrogen atoms. This electron-deficient structure enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), serving as a key scaffold in bioconjugation and medicinal chemistry. Its bench-stable nature facilitates reliable use in diverse synthetic workflows.

Application

2H-1,2,3-Triazole serves as a stable, bench-ready heterocyclic building block for click chemistry and medicinal chemistry applications. Its regioselective reactivity enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating rapid access to triazole-linked conjugates. The functional group tolerance and metabolic stability of the triazole ring make it a valuable scaffold in drug discovery and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   -0.1953
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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