(R)-Chroman-4-amine hydrochloride

Name: (R)-Chroman-4-amine hydrochloride
Brand: ChemScene
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CAS No. 730980-59-3
Cat. No. CS-0060637
Purity≥97%
MDL No.MFCD08457629

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-Chroman-4-amine hydrochloride|CS-0060637

Structure of 730980-59-3

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Description

(R)-Chroman-4-amine hydrochloride is a chiral amine scaffold featuring a rigid chroman core with defined stereochemistry at the 4-position. This bench-stable salt delivers a nucleophilic amine functionality suitable for asymmetric synthesis, peptide coupling, and ligand development in medicinal chemistry workflows.

Application

(R)-Chroman-4-amine hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard amine functionalization. Its bench-stable hydrochloride salt form facilitates handling and purification, while the (R)-configured chroman scaffold provides stereochemical control in target-directed synthesis. Functions effectively in coupling reactions, reductive amination, and cyclization protocols common to API development.

General Information

CAS No. 730980-59-3
Cat. No. CS-0060637
Purity ≥97%
MDL No. MFCD08457629
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₂ClNO
Molecular Weight 185.65
Synonym(s) (R)-CHROMAN-4-YLAMINE HYDROCHLORIDE
SMILES N[C@@H]1CCOC2=C1C=CC=C2.Cl

Computational Chemistry Data

TPSA 35.25
LogP 1.8907
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Other aromatic heterocycles compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-Chroman-4-amine hydrochloride

CAS No. 730980-59-3

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