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CS-W001157 4
Total: USD 88.00

1-(2-Pyridinyl)ethanamine

  • CAS No. 42088-91-5

  • Cat. No. CS-M2153
  • Purity≥95%
  • MDL No.MFCD05215238

*For research and further manufacturing use only, not for direct human use.

1-(2-Pyridinyl)ethanamine|CS-M2153

Structure of 42088-91-5

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General Information

  • CAS No. 42088-91-5
  • Cat. No. CS-M2153
  • Purity ≥95%
  • MDL No. MFCD05215238
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂
  • Molecular Weight 122.17
  • Synonym(s) alpha-Pyridylethylamine
  • SMILES NC(C1=NC=CC=C1)C

Description

1-(2-Pyridinyl)ethanamine features a pyridine ring linked via an ethyl bridge to a primary amine group, enabling versatile coordination in catalysis and ligand design. This bench-stable, moisture-tolerant compound integrates readily into synthetic pathways requiring nitrogen-donor functionality.

Application

1-(2-Pyridinyl)ethanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through straightforward functionalization at the amine and pyridine moieties. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of pharmaceutical intermediates and ligands for transition metal catalysis.

Synthesis

  • Route1
    • 1-(Pyridin-2-yl)ethanone  Imatinib Impurity|CS-0167014
      1122-62-9
    • ~58%
    • In-stock
      1-(2-Pyridinyl)ethanamine|CS-M2153
      42088-91-5

    References

    • SIGNAL PHARMACEUTICALS, LLC Patent: WO2008/51493 A2, 2008 ; Location in patent: Page/Page column 105 ;
  • Route2
    • (E)-1-(Pyridin-2-yl)ethan-1-oneoxime|CS-0170831
      79462-42-3
    • ~95%
    • In-stock
      1-(2-Pyridinyl)ethanamine|CS-M2153
      42088-91-5

    References

    • Brunner, Henri; Niemetz, Markus Monatshefte fur Chemie, 2002 , vol. 133, # 2 p. 115 - 126
  • Route3
    • null|null
      75-16-1
    • ~%
    • In-stock
      1-(2-Pyridinyl)ethanamine|CS-M2153
      42088-91-5

    References

    • Aslanian, Robert G.; Bennett, Chad E.; Burnett, Duane A.; Chan, Tin-Yau; Kiselgof, Eugenia Y.; Knutson, Chad E.; Harris, Joel M.; McKittrick, Brian A.; Palani, Anandan; Smith, Elizabeth M.; Vaccaro, Henry M.; Xiao, Dong; Kim, Hyunjin M. Patent: US2008/76751 A1, 2008 ; Location in patent: Page/Page column 111 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H227-H301-H315-H318-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.1013
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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