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CS-W001157 4
Total: USD 88.00

(R)-Pyrrolidine-3-carboxylic acid

  • CAS No. 72580-54-2

  • Cat. No. CS-D1771
  • Purity≥95%
  • MDL No.MFCD08272856

*For research and further manufacturing use only, not for direct human use.

(R)-Pyrrolidine-3-carboxylic acid|CS-D1771

Structure of 72580-54-2

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General Information

  • CAS No. 72580-54-2
  • Cat. No. CS-D1771
  • Purity ≥95%
  • MDL No. MFCD08272856
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NO₂
  • Molecular Weight 115.13
  • Synonym(s) None
  • SMILES OC([C@@H]1CCNC1)=O

Description

(R)-Pyrrolidine-3-carboxylic acid features a chiral pyrrolidine core with a carboxylic acid group at the 3-position, offering high enantiomeric purity for asymmetric synthesis. This bench-stable scaffold integrates readily into peptidomimetics and bioactive molecules, providing structural rigidity and favorable hydrogen-bonding capacity in medicinal chemistry applications.

Application

(R)-Pyrrolidine-3-carboxylic acid serves as a stereochemically defined building block for the synthesis of bioactive heterocycles and peptidomimetics. Its well-established conformational rigidity and carboxylic acid functionality enable efficient incorporation into medicinal chemistry libraries, facilitating coupling reactions and hydrogen bonding interactions in target-directed design. The compound exhibits excellent bench stability and ease of purification, supporting scalable applications in synthetic organic chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   -0.3195
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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