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CS-W001157 4
Total: USD 88.00

4-Bromo-6-methoxy-1,5-naphthyridin-3-amine

  • CAS No. 724788-66-3

  • Cat. No. CS-0455261
  • Molecule weight254.08
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-6-methoxy-1,5-naphthyridin-3-amine|CS-0455261

Structure of 724788-66-3

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General Information

  • CAS No. 724788-66-3
  • Cat. No. CS-0455261
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈BrN₃O
  • Molecular Weight 254.08
  • Synonym(s) 4-Bromo-6-methoxy-1,5phthyridin-3-ylamine
  • SMILES COC1=NC2=C(C=C1)N=CC(=C2Br)N

Synthesis

  • Route1
    • 4-Bromo-6-methoxy-1,5-naphthyridine-3-carboxylic acid|CS-0366774
      724788-65-2
    • null|null
      75-65-0
    • ~%
    • 4-Bromo-6-methoxy-1,5-naphthyridin-3-amine|CS-0455261
      724788-66-3
    • null|null
      724788-67-4

    References

    • GLAXO GROUP LIMITED Patent: WO2006/17468 A2, 2006 ; Location in patent: Page/Page column 22 ;
  • Route2
    • null|null
      724788-67-4
    • ~73%
    • 4-Bromo-6-methoxy-1,5-naphthyridin-3-amine|CS-0455261
      724788-66-3

    References

    • GLAXO GROUP LIMITED Patent: WO2006/17468 A2, 2006 ; Location in patent: Page/Page column 22 ;
  • Route3

    References

    • Miles, Timothy J.; Axten, Jeffrey M.; Barfoot, Christopher; Brooks, Gerald; Brown, Pamela; Chen, Dongzhao; Dabbs, Steven; Davies, David T.; Downie, David L.; Eyrisch, Susanne; Gallagher, Timothy; Giordano, Ilaria; Gwynn, Michael N.; Hennessy, Alan; Hoover, Jennifer; Huang, Jianzhong; Jones, Graham; Markwell, Roger; Miller, William H.; Minthorn, Elizabeth A.; Rittenhouse, Stephen; Seefeld, Mark; Pearson, Neil Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 24 p. 7489 - 7495

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   61.03
  • LogP   1.9831
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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