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CS-W001157 4
Total: USD 88.00

1,8-Naphthyridine

  • CAS No. 254-60-4

  • Cat. No. CS-W002277
  • Purity≥97%
  • MDL No.MFCD00059751

*For research and further manufacturing use only, not for direct human use.

1,8-Naphthyridine|CS-W002277

Structure of 254-60-4

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General Information

  • CAS No. 254-60-4
  • Cat. No. CS-W002277
  • Purity ≥97%
  • MDL No. MFCD00059751
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂
  • Molecular Weight 130.15
  • Synonym(s) 1,8-Diazanaphthalene
  • SMILES N=1C=CC=C2C=CC=NC12

Description

1,8-Naphthyridine is a heterocyclic aromatic compound featuring two nitrogen atoms at the 1 and 8 positions, conferring enhanced basicity and coordination potential. This scaffold integrates readily into ligand design for transition metal catalysis and serves as a core motif in bioactive molecule synthesis. Its planar structure supports π-stacking interactions, making it valuable in supramolecular chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Zhichkin, Pavel; Beer, Catherine M. Cillo; Rennells, W. Martin; Fairfax, David J. Synlett, 2006 , # 3 p. 379 - 382
  • Route2

    References

    • Monatshefte fur Chemie, , vol. 127, # 4 p. 391 - 396
  • Route3
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      37960-59-1
    • ~%
    • In-stock
      1,8-Naphthyridine|CS-W002277
      254-60-4

    References

    • Australian Journal of Chemistry, , vol. 34, # 1 p. 163 - 170

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   1.6298
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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