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CS-W001157 4
Total: USD 88.00

8-Bromo-7-fluoro-2-methoxy-1,5-naphthyridine

  • CAS No. 724788-70-9

  • Cat. No. CS-0089216
  • Molecule weight257.06
  • Purity≥97%
  • MDL No.MFCD09027615

*For research and further manufacturing use only, not for direct human use.

8-Bromo-7-fluoro-2-methoxy-1,5-naphthyridine|CS-0089216

Structure of 724788-70-9

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General Information

  • CAS No. 724788-70-9
  • Cat. No. CS-0089216
  • Purity ≥97%
  • MDL No. MFCD09027615
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆BrFN₂O
  • Molecular Weight 257.06
  • Synonym(s) None
  • SMILES COC1=NC2=C(Br)C(F)=CN=C2C=C1

Synthesis

  • Route1
    • 4-Bromo-6-methoxy-1,5-naphthyridin-3-amine|CS-0455261
      724788-66-3
    • ~%
    • In-stock
      8-Bromo-7-fluoro-2-methoxy-1,5-naphthyridine|CS-0089216
      724788-70-9

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 24 p. 7489 - 7495
  • Route2
    • 3-Fluoro-6-methoxy-1,5-naphthyridin-4-ol|CS-0131400
      1075259-77-6
    • ~%
    • In-stock
      8-Bromo-7-fluoro-2-methoxy-1,5-naphthyridine|CS-0089216
      724788-70-9

    References

    • ACTELION PHARMACEUTICALS LTD; ABELE, Stefan; MEIER, Hans; SCHMIDT, Gunther; STEINER, Heinz Patent: WO2013/160875 A1, 2013 ; Location in patent: Page/Page column 26 ;
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 24 p. 7489 - 7495

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.01
  • LogP   2.54
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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