tert-Butyl ((3S,4R)-3-hydroxypiperidin-4-yl)carbamate

Name: tert-Butyl ((3S,4R)-3-hydroxypiperidin-4-yl)carbamate
Brand: ChemScene
Availability: InStock
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CAS No. 724787-35-3
Cat. No. CS-0058547
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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tert-Butyl ((3S,4R)-3-hydroxypiperidin-4-yl)carbamate|CS-0058547

Structure of 724787-35-3

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Description

tert-Butyl ((3S,4R)-3-hydroxypiperidin-4-yl)carbamate is a stereochemically defined piperidine derivative featuring a protected hydroxyl group and a carbamate handle. This bench-stable scaffold integrates readily into complex molecular architectures, enabling efficient access to bioactive compounds through selective functionalization at the C3 position.

Application

tert-Butyl ((3S,4R)-3-hydroxypiperidin-4-yl)carbamate serves as a stereochemically defined building block for the synthesis of bioactive piperidine derivatives. The (3S,4R)-configuration provides predictable stereoselectivity in downstream transformations, while the tert-butyl carbamate group offers stability and convenient deprotection under mild acidic conditions. Its hydroxyl functionality enables efficient derivatization via esterification, etherification, or oxidation to ketone, supporting diverse scaffold elaboration in medicinal chemistry campaigns.

General Information

CAS No. 724787-35-3
Cat. No. CS-0058547
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₂₀N₂O₃
Molecular Weight 216.28
Synonym(s) tert-butyl N-[(3S,4R)-3-hydroxypiperidin-4-yl]carbamate
SMILES O[C@@H]1[C@H](NC(OC(C)(C)C)=O)CCNC1

Computational Chemistry Data

TPSA 70.59
LogP 0.2339
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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tert-Butyl ((3S,4R)-3-hydroxypiperidin-4-yl)carbamate

CAS No. 724787-35-3

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