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CS-W001157 4
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(R)-tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate

  • CAS No. 138108-72-2

  • Cat. No. CS-D0746
  • Purity≥95%
  • MDL No.MFCD03094725

*For research and further manufacturing use only, not for direct human use.

(R)-tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate|CS-D0746

Structure of 138108-72-2

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General Information

  • CAS No. 138108-72-2
  • Cat. No. CS-D0746
  • Purity ≥95%
  • MDL No. MFCD03094725
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₃
  • Molecular Weight 201.26
  • Synonym(s) (R)-1-Boc-3-(hydroxymethyl)pyrrolidine
  • SMILES O=C(OC(C)(C)C)N(CC1)C[C@@H]1CO

Synthesis

  • Route1

    References

    • WO2011/150198 A1, ; Page/Page column 151 ; WO 2011/150198 A1
  • Route2

    References

    • US2013/184313 A1, ; Paragraph 1653; 1654 ;
  • Route3
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • ((R)-1-((R)-1-Phenylethyl)pyrrolidin-3-yl)methanol|CS-0207902
      99735-47-4
    • ~97%
    • In-stock
      (R)-tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate|CS-D0746
      138108-72-2

    References

    • Journal of Medicinal Chemistry, , vol. 42, # 4 p. 677 - 690

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.77
  • LogP   1.2357
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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