(R)-(1-Methylpyrrolidin-3-yl)methanol

Name: (R)-(1-Methylpyrrolidin-3-yl)methanol
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CAS No. 1210935-33-3
Cat. No. CS-D0333
Purity≥98%
MDL No.MFCD17015956

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(R)-(1-Methylpyrrolidin-3-yl)methanol|CS-D0333

Structure of 1210935-33-3

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Description

(R)-(1-Methylpyrrolidin-3-yl)methanol is a chiral building block featuring a stereodefined pyrrolidine ring with a methanol substituent at the 3-position. This configuration imparts favorable solubility and metabolic stability, enabling its use in asymmetric synthesis and medicinal chemistry. The molecule integrates readily into bioactive scaffolds due to its polar, hydrogen-bonding functionality and defined stereochemistry.

Application

(R)-(1-Methylpyrrolidin-3-yl)methanol serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide-like scaffolds. Its bench-stable pyrrolidine core exhibits excellent functional group tolerance and facilitates stereoselective transformations. The primary alcohol functionality supports direct derivatization or protection strategies, while the adjacent chiral center ensures predictable stereochemical outcomes in coupling reactions and cyclizations.

General Information

CAS No. 1210935-33-3
Cat. No. CS-D0333
Purity ≥98%
MDL No. MFCD17015956
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO
Molecular Weight 115.17
Synonym(s) [(3R)-1-methylpyrrolidin-3-yl]methanol
SMILES OC[C@H]1CN(C)CC1

Computational Chemistry Data

TPSA 23.47
LogP -0.0696
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS02
Signal Word : Danger	UN#: 1993
Class : 3	Packing Group : Ⅲ
Hazard Statements : H225
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-(1-Methylpyrrolidin-3-yl)methanol

CAS No. 1210935-33-3

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