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tert-Butyl (3S,4R)-4-amino-3-hydroxypiperidine-1-carboxylate

  • CAS No. 1523530-36-0

  • Cat. No. CS-0048537
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3S,4R)-4-amino-3-hydroxypiperidine-1-carboxylate|CS-0048537

Structure of 1523530-36-0

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General Information

  • CAS No. 1523530-36-0
  • Cat. No. CS-0048537
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀N₂O₃
  • Molecular Weight 216.28
  • Synonym(s) (3S,4R)-tert-Butyl 4-amino-3-hydroxypiperidine-1-carboxylate
  • SMILES CC(C)(C)OC(=O)N1CC[C@@H](N)[C@@H](O)C1

Description

tert-Butyl (3S,4R)-4-amino-3-hydroxypiperidine-1-carboxylate features a stereochemically defined piperidine core with complementary amine and hydroxyl functionalities. This bench-stable derivative enables direct incorporation into complex molecular architectures, offering precise control over spatial orientation in medicinal chemistry and peptide mimicry applications.

Application

tert-Butyl (3S,4R)-4-amino-3-hydroxypiperidine-1-carboxylate serves as a stereochemically defined building block for the synthesis of bioactive piperidine scaffolds. The protected amine and hydroxyl groups enable orthogonal functionalization, while the stable tert-butyl carbamate facilitates purification and compatibility with diverse coupling reactions. Its well-defined stereochemistry supports efficient access to complex heterocycles relevant in medicinal chemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.79
  • LogP   0.3154
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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