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CS-W001157 4
Total: USD 88.00

4-Bromo-3-fluorobenzenesulfonyl chloride

  • CAS No. 351003-51-5

  • Cat. No. CS-W012343
  • Purity≥97%
  • MDL No.MFCD03094150

*For research and further manufacturing use only, not for direct human use.

4-Bromo-3-fluorobenzenesulfonyl chloride|CS-W012343

Structure of 351003-51-5

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General Information

  • CAS No. 351003-51-5
  • Cat. No. CS-W012343
  • Purity ≥97%
  • MDL No. MFCD03094150
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrClFO₂S
  • Molecular Weight 273.51
  • Synonym(s) None
  • SMILES O=S(C1=CC=C(Br)C(F)=C1)(Cl)=O

Description

Chlorogenic acid is used as a food additive in coffee products, chewing gum and mint. It acts as an intermediate in the biosynthesis of lignin, which is an antioxidant.

Application

4-Bromo-3-fluorobenzenesulfonyl chloride serves as a versatile sulfonylating agent for the synthesis of sulfonamide derivatives. Its ortho-fluoro and para-bromo substituents enhance electrophilic reactivity while enabling downstream functionalization via cross-coupling. The reagent exhibits excellent bench stability, facilitates clean reactions with amines under mild conditions, and is compatible with diverse functional groups, making it ideal for constructing bioactive sulfonamide scaffolds in medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   2.5157
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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